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. Author manuscript; available in PMC: 2026 Jun 2.
Published in final edited form as: Adv Neurobiol. 2026;48:151–190. doi: 10.1007/978-3-032-12594-1_6

Figure 10: Structural models for regulation of the TEN/ADGRL interaction by alternative splicing.

Figure 10:

A, B: In the absence of the SSB insert, each TENSF can explore the synaptic cleft and find ADGRL molecules to interact with. C, D: In the presence of SSB insert, the two TENSF are locked together and cannot explore the synaptic space to bind to post-synaptic ADGRLs.