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. Author manuscript; available in PMC: 2026 Jun 2.
Published in final edited form as: Sleep Med. 2025 Jun 6;133:106607. doi: 10.1016/j.sleep.2025.106607

Fig. 2. Intensity, locality and control in hypersomnolence pathophysiology.

Fig. 2.

The figure summarizes the proposed categorization of hypersomnolence pathophysiological mechanisms along three main axes: intensity (ranging from physiological through excessive), locality (ranging from local through global neural circuits), and control (ranging from predominantly homeostatic to predominantly circadian). The circadian/homeostatic control picture is taken from Ref. [159] (CC-BY license).