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. Author manuscript; available in PMC: 2026 Jun 2.
Published in final edited form as: Sleep Med. 2025 Jun 6;133:106607. doi: 10.1016/j.sleep.2025.106607

Table 2.

Differences between Mean Sleep Latency Test and Maintenance of Wakefulness test.

MSLT MWT
Measure of sleep resistance *
Measure of sleep propensity *
Pathological values ≤8 min ≤19 min
Measure of REM sleep intrusion *
PSG night before Mandatory Recommended
Sensitivity to sleep deprivation ** **
Fitness to drive **
Diagnosis of narcolepsy *
Treatment response (drugs, behavior, CPAP) **
Correlation with ESS Weak to moderate Weak to moderate
Correlation with reaction tests Weak to moderate Moderate to strong

The number of stars indicates the appropriateness of test for each of the items. MSLT, multiple sleep latency test. MWT, maintenance of wakefulness test. REM, rapid-eye-movement. PSG, polysomnography. CPAP, continuous positive airway pressure. ESS, excessive daytime sleepiness.