Table 3.

Hypersomnolence in neurological disorders.

Neurological Disorder	Hypersomnolence	Fatigue	Remarks	References
Parkinson’s disease	20–40 %	30–70 %	Apathy in 10 %	[84–88]
Alzheimer disease	20–50 %			[147]
Stroke	20–40 %	40–60 %	Often ENS in thalamic/sub-cortical stroke.	[78–80]
Epilepsy	20–30 %			[148,149]
Multiple Sclerosis	10–20 %	>70 %	Rarely symptomatic narcolepsy	[89,90,150]
Neuromuscular disorders	20–40 %	40–60 %		[151,152]
Autoimmune/paraneoplastic	28 %	61–65 %		[153,154]
Migraine/headache	20–40 %			[155]
Narcolepsy	>95 %	>70 %		[156,157]
Idiopathic hypersomnia	>95 %	>70 %		[2]
RLS	10–20 %	20–40 %		[158]

RLS: restless legs syndrome; ENS: excessive need for sleep.