Table 4.

Evidence grade of the conclusion based on GRADE.

Outcome	No.of studies (effects)	Design	Total sample size (n)	Effect estimate (95% CI)	Risk of bias	Inconsistency	Indirectness	Imprecision	Other considerations	Quality
Global cognition	10	randomized trials	749	0.49 [0.25 to 0.73]	Not serious	Serious	Not serious	Not serious	None	Moderate
TMT-based executive/attention-related performance	1	randomized trials	66	0.5 [0.15 to 0.84]	Not serious	Not serious	Not serious	Serious	None	Low
Functional mobility	5	randomized trials	507	0.39[0.05 to 0.73]	serious	Serious	Not serious	Not serious	None	Low