Table 2. Vibrio spp. genetic and phenotypic antimicrobial resistance profiles.
| Isolate (strain) | Origin (year) | Antibiogram phenotype (corresponding genotype)* | Additional markers† |
|---|---|---|---|
| V. cholerae O1, classical (9060–79) | ATCC 14035 (1949) | Pan susceptible | tetC, vceA, vceB, vcaM, vcmA |
| V. cholerae O1, El Tor (1029–84) | Florida (1984) | AM‡ | vceA, vceB, vcaM, vcrM |
| V. cholerae O1, El Tor (C6607T1)§ | Malawi (1990) | C(vceA, vceB), SXT(dfrA15, suIII), G(suII, suIII), S(strA, strB, vcmA), AM | qacEΔ1, tetC, vcrM |
| V. cholerae O139 (F851) | Bangladesh (1993) | SXT(dfrA18, suIII), G(suIII), S(strA, strB, vcmA), C†(floR, vceA, vceB), FX, AM‡ | vcrM |
| V. cholerae O1, El Tor (3500–96) | Guatemala (1996) | G(suII), S(aadA1, aadA2, vcmA), FX, AM‡ | qacEΔ1, vceA, vceB, vcrM |
| V. cholerae O1, El Tor (3517–97) | China (1997) | TE(tetA), G(suIII), S(strA, strB, vcmA), FX | floR, vceA, vceB, vcrM |
| V. cholerae O1, El Tor (3517–98) | India (1998) | SXT(dfrA1, suIII), NA(vceA, vceB), G(suIII), S(strA, strB, vcmA), FX | floR, vcrM |
| V. cholerae O139 (K0020)§ | Hong Kong (2000) | SXT(drfA12, dfrA18, suIII), TE(tetD), G(suII, suIII), S(aadA2, strA, strB, vcmA), K(aphA1, vcmA) | floR, qacEΔ1, vceA, vceB, vcrM |
| V. cholerae O1, El Tor (K0007) | Bangladesh (2003) | SXT(dfrA1, suIII), NA(vceA, vceB), G(suIII), S(strA, strB, vcmA), FX | floR, vcrM |
Antibiotics: ampicillin (AM), chloramphenicol (C), cephalothin (CF), furazolidone (FX), sulfisoxazole (G), kanamycin (K), nalidixic acid (NA), streptomycin (S), SXT, tetracycline (TE).
*
Combined, the entire antimicrobial resistance profile for each strain has been presented
†
Genes that were present (hybridization positive) in the microarray analyses but whose corresponding phenotype was not found or was not tested for in the antibiogram analyses
‡
Intermediate resistance
§
Microarray hybridization profiles presented in Fig. 1