Table 1. Effect of corticosterone on frequency, amplitude, and decay time of mEPSCs in CA1 hippocampal neurons.
Condition | mEPSC frequency, Hz | mEPSC amplitude, pA | τ of decay, s |
---|---|---|---|
Before corticosterone | 0.85 ± 0.14 | 22.8 ± 2.3 | 17.5 ± 1.6 |
During corticosterone | 1.33 ± 0.25* | 24.5 ± 1.9 | 15.8 ± 0.4 |
All values represent the mean ± SEM, based on a total of 3,242 events from five cells. Corticosterone significantly (*, P < 0.05) enhanced the mEPSC frequency (determined between 5 and 10 min after application was started), whereas the amplitude and time constant of the decay (based on a monoexponential fit) remained unaffected. Control data were collected between 5 and 0 min before corticosterone application was started.