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[Preprint]. 2026 May 27:2026.05.22.727303. [Version 1] doi: 10.64898/2026.05.22.727303

Figure 5: In vivo imaging window assessment of lead fluorophores 25–25 and 25–26.

Figure 5:

(a) Average WMTs in vivo intensity for lead fluorophores after various timepoints following intravenous administration, n=4. (b) Average white-matter-to-gray-matter tissue intensity ratios for lead fluorophores at different timepoints following intravenous administration, n=4. Average SBRs were compared to a 4-hour timepoint vehicle-injected control with a one-way ANOVA using Geisser-Greenhouse correction followed by a Fisher’s LSD multiple comparison test, where 1, 2, 3 and 4 asterisks represent P values less than 0.05, 0.01, 0.001, and 0.0001 respectively. (c) Representative white light and fluorescence images of the coronal section at various timepoints for lead fluorophores, images are displayed with autocontrast adjustment for visualization.