Skip to main content
. 2026 Jun 2;14:e21252. doi: 10.7717/peerj.21252

Table 2. GRADE summary of evidence.

Certainty assessment No of patients Effect Certainty Importance
No of studies Study design Risk of bias Inconsistency Indirectness Imprecision Other considerations (EXP) (CON) Relative
(95% CI)
Absolute
(95% CI)
Body composition
24 RT Seriousa Seriousb Not serious Not serious None 322 314 – SMD 0.66 SD lower
(0.91 lower to 0.41 lower)
⊕⊕〇〇
Lowa,b
IMPORTANT
Change of direction ability
5 RT Seriousa Not serious Not serious Seriousc None 59 55 – MD 0.27 s lower
(0.41 lower to 0.13 lower)
⊕⊕〇〇
Lowa,c
IMPORTANT
Aerobic capacity
13 RT Seriousa Very seriousd Not serious Not serious None 213 201 – MD 3.66 ml/kg/min higher
(2.67 higher to 4.65 higher)
⊕〇〇〇
Very lowa,d
CRITICAL
Anaerobic capacity
8 RT Seriousa Not serious Not serious Seriouse None 62 86 – MD 37.36 W higher
(22.3 higher to 52.42 higher)
⊕⊕〇〇
Lowa,e
CRITICAL
Sprint ability
12 RT Seriousa Seriousf Not serious Not serious None 133 110 – MD 0.17 s lower
(0.24 lower to 0.11 lower)
⊕⊕〇〇
Lowa,f
IMPORTANT
Explosive power
17 RT Seriousa Not serious Not serious Not serious None 233 206 – MD 1.55 cm higher
(1.16 higher to 1.95 higher)
⊕⊕⊕〇
Moderatea
CRITICAL

Note:

RT, randomised trials; CI, confidence interval; MD, mean difference; SMD, standardised mean difference; a, Most studies lacked allocation concealment or blinding; b, I2 = 55.9%; c, Only 5 RCTs were included; d, I2 = 82.4%; e, Only 8 RCTs were included; f, I2 = 48.5%; Risk of bias includes issues such as incorrect randomization, lack of allocation concealment, absence of blinding, excessive loss to follow-up, selective outcome reporting, or early termination of the study after observing a beneficial effect. If most of the studies exhibit one or more important risks of bias, the quality of evidence should be downgraded by one level; Inconsistency refers to considerable heterogeneity among studies or a very low p-value in heterogeneity tests. When substantial and unexplained inconsistency is present, the quality of evidence should be downgraded by one level. Indirectness arises when the patients, interventions, comparisons, or outcome measures in the available studies differ from the target PICO elements specified in the review question. If an important degree of indirectness exists, the quality of evidence should be downgraded by one level. Imprecision includes situations with a small sample size, a limited number of included studies, or confidence intervals that include the line of no effect. When evidence is uncertain due to an insufficient sample size or number of events, the quality of evidence should be downgraded by one level. Other considerations include publication bias, a large magnitude of effect, or a dose-response gradient. If there is a strong suspicion of publication bias, the quality of evidence should be downgraded by one level.