Table 1.

Liver and spleen indices among different Schistosoma mansoni-infected mice groups, treated with praziquantel and dapagliflozin as mono- or combined therapy.

Mice groups	Liver index a	Spleen index a
Infected non-treated (n = 6)	7.05 ± 0.79	1.44 ± 0.19
DMSO (n= 5)	6.89 ± 0.29	1.34 ± 0.23
PZQ (n = 6)	5.81 ± 0.97(17.59) *	0.81 ± 0.35(43.75) *
DAPA (n = 5)	6.05 ± 0.23 (14.18) *	1.04 ± 0.05 (27.78) *
DAPA + PZQ (n =  6)	5.86 ± 0.13 (16.88) *	0.83 ± 0.10 (42.36) *
P-value	P = 0.003	P ≤ 0.001

^a Analysis of variance (ANOVA) test. Data are expressed as means ± standard deviation

Values enclosed between parentheses represent the percentage of reduction, compared to infected non-treated group

DAPA: dapagliflozin; DMSO: dimethyl sulfoxide; PZQ: praziquantel

^* Significant difference against infected non-treated, and DMSO-treated groups at P˂ 0.05