Table 3.

Oogram pattern among different Schistosoma mansoni-infected mice groups, treated with praziquantel and dapagliflozin as mono- or combined therapy.

Mice groups	Oogram pattern
	Immature % a	Mature % a	Dead % a
Infected non-treated (n = 6)	61.58 ± 11.17	38.42 ± 11.17	0 ± 0
DMSO (n = 5)	59.13 ± 5.15	38.07 ± 5.32	2.80 ± 1.27
PZQ (n = 6)	7.60 ± 4.45 *	42.92 ± 4.25	49.48 ± 4.51 *
DAPA (n= 5)	55.42 ± 9.81	34.33 ± 7.01	10.25 ± 4.33
DAPA + PZQ (n = 6)	5.88 ± 9.12 *	49.91 ± 14.17 **	44.21 ± 17.15 *
P-value	P = 0.092	P ≤ 0.001	P≤ 0.001

^a Analysis of variance (ANOVA) test. Data are expressed as means ± standard deviation

DAPA: dapagliflozin; DMSO: dimethyl sulfoxide; PZQ: praziquantel

^* Significant difference against infected non-treated, DMSO-, and DAPA-treated groups at P˂ 0.001

^** Significant difference against infected non-treated, DMSO-, and DAPA-treated groups at P˂ 0.05