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. 2026 May 25;7:1770257. doi: 10.3389/fragi.2026.1770257

TABLE 3.

Spearman correlation between serum biomarkers and sarcopenia components.

Parameter Correlation coefficient (r) p-value
SMI and CRP −0.462 <0.001
Grip strength and CRP −0.435 <0.001
Gait speed and CRP −0.312 0.015
SMI and TNF-α −0.397 0.0016
Grip strength and TNF-α −0.211 0.105
Gait speed and TNF-α −0.189 0.148
SMI and IL-6 −0.118 0.369
Grip strength and IL-6 −0.128 0.330
Gait speed and IL-6 −0.094 0.476
SMI and IGF-1 −0.087 0.507
Grip strength and IGF-1 −0.060 0.651
Gait speed and IGF-1 −0.073 0.579

CRP, C-reactive protein; IL-6, Interleukin-6, TNF-α, Tumor Necrosis Factor-alpha; IGF-1, Insulin-like Growth Factor 1; SMI, skeletal muscle index.