Table 2.

Total number of nodes and edges in the co-expression and PPI networks before and after filtration.

	Number of nodes	Number of edges
Co-Expression	22,658	30,455,297
Co-Expression Alpha 0.3	22,630	3,431,798
Filtered Co-Expression	12,873	1,360,160
PPI	23,704	3,285,936
Filtered PPI	12,873	1,275,017
Bipartite Network	25,746	12,873

Co-expression is entirely unfiltered, Co-expression Alpha 0.3 uses filtration factor alpha of 0.3 for preliminary filtration. Filtered Co-expression and Filtered PPI truncates nodes and corresponding edges which are not present in both the co-expression and PPI networks to create the Bipartite Network. Nodes and edges in bipartite network included for posterity. Compute significance scores (alpha) for weighted edges in a NetworkX graph as defined in Serrano et al. 2009¹³², The resulting graph contains only edges that survived from the filtering with the alpha_t threshold. Nota performs a cut of the graph previously filtered through a proprietary function. PPI network was only filtered to match the cs10G2P 1-to-1 map.