Table 2.
Electrocardiogram and echocardiography in the total patient population by country
| Characteristic, n (%) or mean ± SD or median (IQR) | France (883 pts, 9 sites) |
Spain (454 pts, 5 sites) |
Germany (362 pts, 6 sites) |
Italy (287 pts, 4 sites) |
Austria (176 pts, 2 sites) |
p value |
|---|---|---|---|---|---|---|
| Electrocardiogram | ||||||
| Rhythm | < 0.001 | |||||
| Sinus rhythm | 657 (77.8) | 325 (71.7) | 248 (70.5) | 216 (78.5) | 101 (58.4) | |
| Atrial fibrillation | 125 (14.8) | 97 (21.4) | 74 (21.0) | 44 (16.0) | 50 (28.9) | |
| Pacemaker rhythm | 53 (6.3) | 31 (6.8) | 27 (7.7) | 12 (4.4) | 14 (8.1) | |
| Other | 10 (1.2) | 0 (0.0) | 3 (0.9) | 3 (1.1) | 8 (4.6) | |
| AV block second or third degree | 4 (0.5) | 6 (1.3) | 3 (0.9) | 2 (0.7) | 1 (0.6) | 0.544 |
| Left bundle branch block | 85 (10.0) | 53 (11.7) | 42 (11.9) | 27 (9.8) | 31 (17.9) | 0.046 |
| Right bundle branch block | 116 (13.7) | 48 (10.6) | 37 (10.5) | 34 (12.4) | 14 (8.1) | 0.168 |
| Echocardiography | ||||||
| LVEF < 50% | 106 (12.5) | 53 (11.7) | 84 (24.6) | 42 (14.8) | 51 (29.0) | < 0.001 |
| AR, mod/severe | 122 (14.9) | 54 (11.9) | 56 (16.4) | 43 (15.2) | 12 (6.8) | 0.020 |
| AV mean PG (mmHg) |
47.2 ± 12.8 45.0 (41.0, 53.0) |
45.3 ± 11.8 44.5 (40.0, 51.0) |
43.1 ± 16.4 41.0 (32.3, 53.0) |
46.0 ± 13.6 44.0 (39.0, 53.0) |
42.6 ± 14.0 41.5 (34.0, 48.8) |
< 0.001 |
| AV peak PG (mmHg) |
71.6 ± 18.3 70.0 (61.0, 81.0) |
74.6 ± 18.3 73.5 (65.0, 83.0) |
69.5 ± 24.1 66.5 (54.0, 85.0) |
72.8 ± 19.2 71.0 (62.5, 82.0) |
71.3 ± 20.5 70.0 (60.0, 80.0) |
< 0.001 |
| Vmax (m/s) |
4.1 ± 0.9 4.2 (3.9, 4.5) |
4.3 ± 0.6 4.4 (4.1, 4.7) |
4.0 ± 0.8 4.0 (3.6, 4.4) |
4.2 ± 0.8 4.2 (4.0, 4.5) |
4.2 ± 0.6 4.2 (3.9, 4.4) |
< 0.001 |
| AVA (cm2) |
0.8 ± 0.4 0.8 (0.6, 0.9) |
0.8 ± 0.2 0.7 (0.6, 0.9) |
0.7 ± 0.2 0.7 (0.6, 0.9) |
0.7 ± 0.2 0.8 (0.6, 0.9) |
0.8 ± 0.2 0.7 (0.6, 0.9) |
0.002 |
| Indexed AVA (cm2/m2) |
0.4 ± 0.2 0.4 (0.4, 0.5) |
0.4 ± 0.1 0.4 (0.4, 0.5) |
0.4 ± 0.1 0.4 (0.3, 0.5) |
0.4 ± 0.1 0.4 (0.3, 0.5) |
0.4 ± 0.1 0.4 (0.3, 0.5) |
< 0.001 |
AR aortic regurgitation, AV aortic valve, AVA aortic valve area, IQR interquartile range, LVEF left ventricular ejection fraction, PG pressure gradient, SD standard deviation, pts patients