Table 4.
Assessment of additional predictors and their association with the primary event
| Explanatory variables | HR | 95%CI | p value |
|---|---|---|---|
| Sex | |||
| Female | Ref | ||
| Male | 1.60 | [1.14; 2.26] | 0.007 |
| Moderate-severe valve dysfunction | |||
| None | Ref | ||
| Aortic regurgitation | 15.25 | [7.08;32.85] | <0.001 |
| Aortic stenosis | 22.56 | [11.41;44.63] | <0.001 |
| Aortic stenosis and regurgitation | 29.09 | [13.63;60.74] | <0.001 |
| Aortic dilatation | |||
| < 39 mm | Ref | ||
| > 39 mm | 1.23 | [0.89; 1.70] | 0.2 |
| Raphe | |||
| None | Ref | ||
| Visible raphe | 0.94 | [0.70; 1.31] | 0.8 |
| Coarctation of the aorta | |||
| Absent | Ref | ||
| Present | 0.72 | [0.40; 1.32] | 0.3 |
Univariate delayed-entry Cox regression analyses predicting the age-related hazard of surgery of the aortic valve or proximal aorta. Coarctation of the aorta is included regardless of repair status. P values from Wald’s test
HR hazard ratio, CI confidence interval