Table 1.
Demographics and clinical characteristics of patients enrolled in the present study
| Feature | Description |
|---|---|
| No. of patients | 154 |
| Sex (females/males), n | 99/54 |
| Ethnicity | White (n = 86) |
| Hispanic (n = 47) | |
| Arab (n = 15) | |
| Black (n = 4) | |
| Southeast Asia (n = 1) | |
| South Asia (n = 1) | |
| Age at onset, years (mean ± SD) | 44.67 ± 17.67 |
| Age at diagnosis, years (mean ± SD) | 45.52 ± 17.59 |
| Diagnostic delay, years (median [IQR]) | 0.00 [0.50] |
| Laterality | Unilateral (n = 90) |
| Bilateral (n = 64) | |
| Anatomic pattern (no. of eyes) | Anterior scleritis (n = 151) |
| Diffuse (n = 96) | |
| Nodular (n = 33) | |
| Necrotizing (n = 7) | |
| - Necrotizing with inflammation (n = 6) | |
| - Necrotizing without inflammation/scleromalacia perforans (n = 1) | |
| Not reported (n = 15) | |
| Posterior scleritis (n = 37) | |
| Anatomical classification unavailable for 30 eyes | |
| Concomitant uveitis (no. of patients) | n = 28 |
| Concomitant PUK (no. of patients) | n = 14 |
| HLA typing | HLA-B*27 positivity (n = 3) |
| HLA-B*51 positivity (n = 6) | |
| HLA-Cw6 positivity (n = 1) | |
| HLA-DRB1 positivity (n = 2) |
HLA Human leukocyte antigen, IQR interquartile range, PUK peripheral ulcerative keratitis, SD standard deviation