Table 2.
Variables predicting the development of ocular complications in scleritis and their respective significance in univariate and regression analysis
| Univariate analysis | |
|---|---|
| Variable | p value |
| Sex | 0.128 |
| Associated systemic disease | 0.183 |
| GPA | < 0.0001* |
| Autoantibodies | 0.074 |
| Laterality | 0.132 |
| Concomitant uveitis | 0.023* |
| Anatomic pattern | 0.172 |
| Topical and/or oral GCs | 0.020* |
| cDMARDs | 0.551 |
| Biotechnological agents | 0.311 |
| Regression analysis | ||||
|---|---|---|---|---|
| Variable | OR | Lower CI | Upper CI | p value |
| GPA | 7.747 | 2.891 | 20.759 | < 0.0001 |
| Concomitant uveitis | 3.648 | 1.241 | 10.722 | 0.019 |
| Severity score | 1.138 | 1.003 | 1.290 | 0.044 |
cDMARDs Conventional disease modifying anti-rheumatic drugs, CI confidence interval, GCs glucocorticosteroids, GPA granulomatosis with polyangiitis, OR odds ratio
* indicates statistical significance (p < 0.05)