Why carry out this study

Real-life robust evidence on long-term outcomes in patients with non-infectious scleritis is scarce.

This study aimed at characterizing ocular complications and detecting predictive factors for the development of these complications throughout the disease course.

What was learned from the study

Data from the International Autoinflammatory Diseases Alliance (AIDA) Network revealed that patients with scleritis diagnosed with granulomatosis with polyangiitis and those who present with concomitant uveitis are more likely to develop ocular complications.

The scleritis severity score is an often overlooked but reliable tool capable of predicting the development of ocular complications in patients with scleritis.

Our findings allow more accurate patient profiling and identify a subgroup of patients with scleritis that should undergo tight follow-up control and proper management to preserve long-term visual function.