Table 4.
AnoACE | Length (aa) | Active sites | Hydrophobic C terminus | Predicted GPI anchor |
1‡ | 576 | 1 | No | No |
2 | 638 | 1 | No | No |
3A* | 630 | 1 | No | No |
3B* | 619 | 1 | No | No |
4 | 625 | 1 | No | No |
5† | 619 | 1 | No | No |
6† | 730 | 1 | No | No |
7 | 917 | 1 | Yes | No/marginal |
8‡ | 623 | 1 | No | No |
9 | 1225 | 2 | Yes | Yes |
*AnoACE3A and AnoACE3B are derived from alternative transcripts and differ at their N termini
†AnoACE5 and AnoACE6 are 97% identical, except for an extended C terminus in AnoACE6
‡N-terminus probably missing, no signal peptide