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. 2006 Jan 3;4(1):e32. doi: 10.1371/journal.pbio.0040032

In response to DNA injury, the polymerase Dpo4 inserts a nucleotide, and three of its protein domains (light green, blue, magenta) shift upward (their prior position is shown in gray), while the fourth domain anchors Dpo4. This “bypass replication” maneuver allows DNA replication to proceed error-free.

In response to DNA injury, the polymerase Dpo4 inserts a nucleotide, and three of its protein domains (light green, blue, magenta) shift upward (their prior position is shown in gray), while the fourth domain anchors Dpo4. This “bypass replication” maneuver allows DNA replication to proceed error-free