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Addition of Substituted Anilines to Diphenylacetylene
| % yieldb |
||||
|---|---|---|---|---|
| entry | X | 8/9 | 1b | 2 |
| 1 | H | 3:1 | 98 | 96 (75c) |
| 2 | 4-Me | 4:1 | 79 | 74 |
| 3 | 4-OMe | 7:1 | 31 | 72 (83c) |
| 4 | 4-Cl | 4:1 | >95 | >95 (66c) |
| 5 | 2,6-Me2 | only 8 | 7 | 69 |
Identical results were obtained when the reaction was run in C6D6 or C7D8.
Yields are given as NMR yields. Hydrolysis to the corresponding ketone was used to confirm these assignments.
Isolated yield of the ketone hydrolysis product.
