Table 3.

Mean change in QUALIOST^® scores according to the number of osteoporotic fractures (all types) experienced

No of fracture		0	1	2	≥3
Physical	N	836	272	81	77
	Mean (± 95% CI)	-0.31 (± 1.38)	1.21 (± 2.48)	5.18 (± 4.09)	6.54 (± 4.84)
	Effect Size	-0.02	0.06	0.28	0.30
Emotional	N	838	274	81	77
	Mean (± 95% CI)	-1.55 (± 1.33)	-0.01 (± 2.29)	3.83 (± 3.98)	5.57 (± 3.65)
	Effect Size	-0.08	-0.00	0.21	0.34
Total	N	832	272	81	77
	Mean (± 95% CI)	-0.92 (± 1.25)	0.46 (± 2.18)	4.41 (± 3.73)	5.99 (± 3.72)
	Effect Size	-0.05	0.02	0.26	0.36

Mean change measured between baseline and endpoint

ES = (mean at endpoint – mean at baseline)/standard deviation of change