Table 4.
Comparison of characteristics between the DS group and the Non-DS group
| Feature | DS | Non-DS | X2 | P | |
|---|---|---|---|---|---|
| Missense | Yes(No) | 6(10) | 25(9) | 5.995 | 0.014 |
| Frameshift | Yes(No) | 3(13) | 3(31) | 0.293 | 0.588 |
| Splicing | Yes(No) | 3(13) | 1(33) | 1.859 | 0.173 |
| Nonsense | Yes(No) | 3(14) | 4(31) | 0.3798 | 0.5377 |
| De novo | Yes(No) | 15(1) | 24(9) | 1.78 | 0.182 |
| Fever of first seizure | Yes(No) | 11(5) | 21(13) | 0.23 | 0.631 |
| Status epilepticus | Yes(No) | 9(7) | 9(25) | 4.188 | 0.041 |
| Family history | Yes(No) | 3(13) | 13(21) | 1.898 | 0.168 |
| Cluster seizures | Yes(No) | 10(6) | 18(16) | 0.403 | 0.525 |
| Epilepsy first year EEG abnormalities onset | Yes(No) | 9(7) | 15(19) | 0.642 | 0.423 |
Note: In this study, the total sample size was all greater than 40. When the theoretical frequency was greater than 5, the Pearson chi-square was selected. When the theoretical frequency is ≥ 1 or < 5, continuity correction is selected. When the theoretical frequency is less than 1, look at the Fisher’s exact test; P < 0.05, which was statistically significant