Table 2.
Multivariable-Adjusted Analysis of Factors Associated With ECT Use Among Older Adults With Major Depressive Disordera
| Factor (Reference Group) | Adjusted Odds Ratio | 95% CI | P Value |
|---|---|---|---|
| Age | 0.98 | 0.98–0.98 | < .001 |
| Gender (male) | 0.82 | 0.77–0.87 | < .001 |
| Race/ethnicity (non-Hispanic white) | |||
| Non-Hispanic black | 0.57 | 0.49–0.67 | < .001 |
| Other | 0.76 | 0.65–0.90 | .001 |
| Region (Northeast) | |||
| Midwest | 0.85 | 0.79–0.92 | < .001 |
| South | 0.62 | 0.58–0.67 | < .001 |
| West | 0.58 | 0.53–0.64 | < .001 |
| Median household income (< $40,000) | |||
| $40,000–$59,999 | 1.34 | 1.23–1.46 | < .001 |
| ≥ $60,000 | 1.90 | 1.74–2.06 | < .001 |
| Psychotherapy use | 1.98 | 1.87–2.10 | < .001 |
| ED use | 1.18 | 1.11–1.25 | < .001 |
| Medications prescribed (no) | |||
| Antidepressants | 1.38 | 1.22–1.56 | < .001 |
| Antipsychotics | 5.60 | 5.20–6.04 | < .001 |
| Anxiolytics, sedative/hypnotics | 1.22 | 1.14–1.30 | < .001 |
| Mood stabilizers | 0.77 | 0.72–0.81 | < .001 |
| Lithium | 4.67 | 4.25–5.13 | < .001 |
| Stimulants | 3.34 | 3.03–3.68 | < .001 |
| Behavioral comorbidity (no) | |||
| ADHD and other conduct disorders | 0.68 | 0.60–0.76 | < .001 |
| Anxiety disorder | 1.76 | 1.63–1.89 | < .001 |
| Bipolar disorder | 3.24 | 3.05–3.45 | < .001 |
| Posttraumatic stress disorder | 0.95 | 0.84–1.07 | .368 |
| Schizophrenia | 1.67 | 1.57–1.78 | < .001 |
| Personality disorder | 1.91 | 1.75–2.07 | < .001 |
| Traumatic brain injury and nonpsychotic mental disorders due to brain damage | 0.72 | 0.60–0.85 | < .0001 |
| Alcohol use disorder | 0.91 | 0.82–1.02 | .105 |
| Tobacco use disorder | 0.66 | 0.60–0.72 | < .001 |
| Drug use disorders | 0.97 | 0.89–1.06 | .547 |
Data are from 2014 to 2015 Medicare claims files.
Abbreviations: ADHD = attention-deficit/hyperactivity disorder, ECT = electroconvulsive therapy, ED = emergency department.