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. 2026 May 29;15(11):1005. doi: 10.3390/cells15111005
RA rheumatoid arthritis
NSAIDs non-steroidal anti-inflammatory drugs
DMARDs disease-modifying anti-rheumatic drugs
SIN sinomenine
MTX methotrexate
PSMB9 proteasome subunit beta type-9
LMP2 low molecular mass protein 2
IFN-γ interferon-γ
WGCNA weighted gene co-expression network analysis
RMA robust multi-array average
GO Gene Ontology
KEGG Kyoto Encyclopedia of Genes and Genomes
BP biological process
CC cellular component
MF molecular function
GSEA gene set enrichment analysis
MSigDB Molecular Signatures Database
PPI protein–protein interaction
OA osteoarthritis
CPM counts-per-million
LPS lipopolysaccharide
DEX dexamethasone
TOM topological overlap matrix
FLS fibroblast-like synoviocytes
CFB Complement Factor B