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. 2026 Jun 3;27(11):5058. doi: 10.3390/ijms27115058
PCBs Polychlorinated biphenyls
POPs persistent organic pollutants
CNS central nervous system
NDL-PCBs non-dioxin-like PCBs
DL-PCBs dioxin-like PCBs
AhR aryl hydrocarbon receptor
TCDD 2,3,7,8-tetrachlorodibenzo-p-dioxin
AD Alzheimer Disease
RNA-seq RNA sequencing
DMSO Dimethyl sulfoxide
RA retinoic acid
DEGs differentially expressed genes
GLM generalized linear models
FDR False Discovery Rate
GO Gene Ontology
ORA Over-Representation Analysis
STRING Search Tool for the Retrieval of Interacting Genes/Proteins
PPI protein-protein interaction
CTRL untreated control
PCA Principal Component Analysis
FC Fold Change
BP Biological processes
MF molecular function
CC cellular component
UPS ubiquitin-proteasome system
ALP autophagy-lysosome pathway
sHSPs small heat-shock proteins
ATG autophagy-related proteins
MTT 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay