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. 2026 Jun 2;27(11):5032. doi: 10.3390/ijms27115032
BMI Body Mass Index
CI Confidence Interval
CPB Cumulative Preventable Burden
CpG Cytosine-phosphate-Guanine
DL DerSimonian–Laird
DNA Deoxyribonucleic Acid
EAA Epigenetic Age Acceleration
GRADE Grading of Recommendations, Assessment, Development and Evaluation
HR Hazard Ratio
I2 I-squared (heterogeneity statistic)
MEAB-Index Modifiable Epigenetic Aging Burden Index
MEDLINE Medical Literature Analysis and Retrieval System Online
NOS Newcastle–Ottawa Scale
OR Odds Ratio
PICOS Population, Exposure, Comparator, Outcome, Study design
PMC PubMed Central
PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses
PROSPERO International Prospective Register of Systematic Reviews
RoB 2 Cochrane Risk of Bias 2 tool
SD Standard Deviation
SE Standard Error
SMD Standardized Mean Difference
τ2 Tau-squared (between-study variance)