RPE	Retinal pigment epithelial
ECM	extracellular matrix
EL	ectopia lentis
AL	axial length
Z-AL	Z-score-adjusted axial length
ATN	A: atrophy, T: tractional, and N: neovascular
RT-qPCR	Real Time-quantitative PCR
IF	immunofluorescence staining
WB	Western blotting
ELISA	enzyme-linked immunosorbent assay
RD	retinal detachment
ICL	implantable collamer lens
FBS	fetal bovine serum
PBS	phosphate-buffered saline
SD	standard deviation
NC	healthy control
FAK	focal adhesion kinase
TNF-α	tumor necrosis factor-α
IL-6	interleukin-6
MMP3	matrix metalloproteinase-3
OCT	optical coherence tomography
PCA	Principal component analysis
GO	Gene Ontology
DEGs	differentially expressed genes
KEGG	Kyoto Encyclopedia of Genes and Genomes
PGE2	prostaglandin E2
NF-κB	Nuclear Factor kappa-light-chain-enhancer of activated B cells
MAPK	Mitogen-Activated Protein Kinase
PI3K-Akt	Phosphoinositide 3-kinase/Protein Kinase B
GSEA	Gene Set Enrichment Analysis
HI	haploinsufficiency
DN	dominant-negative