PKM2	Pyruvate kinase muscle type 2
IARC	International Agency for Research on Cancer
DTC	Differentiated thyroid cancer
ATC	Anaplastic thyroid cancer
MTC	Medullary thyroid cancer
PTC	Papillary thyroid cancer
FTC	Follicular thyroid cancer
RAI	Radioactive iodine
RAI-R	RAI-refractory
MKIs	Multi-kinase inhibitors
ORR	Objective response rate
TME	Tumor microenvironment
ROS	Reactive oxygen species
PK	Pyruvate Kinase
PEP	Phosphoenolpyruvate
PKL	Pyruvate kinase liver type
PKR	Pyruvate kinase red blood cell type
PKM1	Pyruvate kinase muscle type 1
3′UTR	3′-untranslated region
PTM	Post-translational modification
O-GlcNAc	O-linked β-N-acetylglucosamine
TRIM35	Tripartite motif-containing protein 35
NSCLC	Non-small cell lung cancer
FBP	Fructose-1,6-bisphosphate
TKT	Transketolase
TCF	T-cell factor
LEF	Lymphoid enhancer factor
EMT	Epithelial–mesenchymal transition
OXPHOS	Oxidative phosphorylation
NIS	Na+-iodine symporter
TAMs	Tumor-associated macrophages
CAFs	Cancer associated fibroblast
DFS	Disease-free survival
OS	Overall survival