Table 2.
Hazard ratios of selected features for osteopenia.
| Feature | Univariate HR | Univariate 95% CI | Univariate P-value | Multivariate HR | Multivariate 95% CI | Multivariate P-value |
|---|---|---|---|---|---|---|
| Age | 1.01 | 1.00-1.02 | 0.010 | 0.99 | 0.98-1.01 | 0.365 |
| Menopause | 20.71 | 9.82-43.66 | <0.001 | 31.5 | 13.85-71.63 | <0.001 |
| UA (umol/L) | 1.00 | 1.00-1.00 | 0.001 | 1.00 | 1.00-1.01 | 0.157 |
| TP (g/L) | 1.04 | 1.02-1.06 | <0.001 | 1.05 | 1.02-1.07 | <0.001 |
| CHOL (mmol/L) | 1.13 | 1.05-1.21 | 0.002 | 0.51 | 0.36-0.72 | <0.001 |
| HDLC (mmol/L) | 1.56 | 1.22-1.99 | <0.001 | 6.32 | 1.88-21.27 | 0.003 |
| LDLC (mmol/L) | 1.13 | 1.04-1.22 | 0.003 | 2.21 | 1.57-3.12 | <0.001 |
| TPINP (ng/mL) | 1.01 | 1.00-1.01 | <0.001 | 1.00 | 0.99-1.00 | 0.132 |
| β-CTX (ng/mL) | 3.04 | 2.26-4.08 | <0.001 | 2.39 | 1.55-3.69 | <0.001 |
| VITD (ng/mL) | 1.02 | 1.02-1.03 | <0.001 | 1.02 | 1.01-1.03 | <0.001 |
| HGB (g/L) | 0.99 | 0.98-1.00 | 0.03 | 0.94 | 0.91-0.97 | <0.001 |
| LYM (×10~9/L) | 1.29 | 1.10-1.52 | 0.002 | 1.00 | 0.51-1.95 | 0.993 |
| MONO (×10~9/L) | 3.97 | 1.87-8.43 | <0.001 | 23.89 | 2.44-234.42 | 0.006 |
The Cox proportional hazard model was used to calculate HR and 95% CI. Multivariable analysis was done based on significant factors from the univariable analysis.