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. 2026 May 29;20:1799391. doi: 10.3389/fnins.2026.1799391

FIGURE 4.

Panel A shows a section of tissue with densely packed cells stained light purple and scattered brown-stained cells indicated by arrows. Panel B displays a brain region with a central area labeled Aβ, showing brown accumulations surrounded by light purple nuclei. Panel C presents brain tissue with two prominent regions labeled Aβ, displaying widespread brown staining against a background of scattered light purple nuclei. Each panel includes a scale bar indicating fifty micrometers.

Cellular staining of VEGFR-1 in 15-month-old Tg2576 mouse brain. (A) Representative image of VEGFR-1 staining (using anti-VEGFR-1 antibody, C’ Ter epitopes, CL0345, Novus Bio) in neurons (black arrow) and EC/microvessel (blue arrow) in hippocampus and (B) VEGFR-1 staining near “cored” amyloid plaques (“Aβ,” using anti-VEGFR-1 antibody CL0345, C’ Ter epitopes, Novus Bio). (C) VEGFR-1 staining (using anti-VEGFR-1 antibody SY09-09, N’-Ter epitopes, Invitrogen) in neurons and the neuropil near amyloid plaques (“Aβ”).