TABLE 1.
Modulation of upregulated genes following Aβ1-42 oligomer treatment by siRNA-mediated VEGFR-1 knockdown.
| Upregulated genes | Aβ(1-42) | Aβ(1-42) + VEGFR-1 Si | |
|---|---|---|---|
| Fold change | P-value | Fold change | |
| Cd14 | 2.997154639 | 0.011378186 | −0.030 |
| Cybb | 1.515474892 | 0.038269181 | −0.050 |
| Il1rap | 1.395450379 | 0.045211798 | |
| Nlrc5 | 2.070456615 | 0.04797841 | −0.352 |
| Trim21 | 2.296919791 | 0.04006894 | −0.337 |
| Irf9 | 1.578945407 | 0.035223581 | −0.114 |
| Ifitm3 | 2.750103986 | 0.011290390 | −3.0147 |
| Parp12 | 2.24902979 | 0.017597679 | −2.520 |
| Zc3hav1 | 2.262801305 | 0.027209517 | −0.646 |
| Ccl9 | 3.004251942 | 0.010003894 | −7.341 |
| Lgals9 | 2.993099182 | 0.012448254 | −5.751 |
| Gadd45b | 2.032433888 | 0.021533132 | −0.373 |
| Hmox1 | 1.880644729 | 0.016092702 | −2.479 |
| Dusp1 | 1.397126194 | 0.045266726 | −0.980 |
| Chchd10 | 1.902407047 | 0.02309212 | 0.339 |
| Npas4 | 2.073243675 | 0.015865994 | |
| Id1 | 2.106559036 | 0.021373972 | −3.846 |
| Gad1 | 1.528439398 | 0.025738308 | |
| Flt1 | 1.6752278011 | 0.012759498 | −3.992 |
Bold values indicate regulation of “genes of interest”.