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The incidence of respiratory symptoms as reported by symptom diary during 7 days following challenge for the safety population
| Symptom / beta2agonist use | Mannitol | Hypertonic Saline |
| n | 627 (%) | 636 (%) |
| Daytime cough | 352 (56.9) | 365 (58.4) |
| Wheeze | 270 (43.6) | 280 (44.8) |
| Trouble breathing | 270 (43.6) | 262 (41.9) |
| Symptoms interfering with activities | 172 (27.8) | 178 (27.4) |
| Night time cough | 212 (34.2) | 236 (37.8) |
| Beta2 agonist use | 319 (51.5) | 333 (53.3) |
| Nebulised beta2 agonist | 16 (2.6) | 19 (3.0) |
