Figure 3. Indel Rate Variation by G+C Content.

(A) Whole genome (blue) and AR (red) averages of indel rates. Error bars denote 95% confidence intervals in ρ as determined by weighted linear regression on log frequencies in the intergap length histogram.

(B) Indel rates per G+C content for individual chromosomes (error bars not included for clarity), and autosomal averages (whole autosome, blue; ARs, red). Most autosomes have undergone similar indel rates, with mildly increased rates for the small chromosomes (22 and 19 in particular), and a marked reduction for X, as expected by its distinct germline history. Because of its size, measurements on the Y chromosome lack accuracy, but are consistent with an increase in indel rates.