Table 3.
Comparison of results obtained with the SSOP-ELISA (horizontal) and RFLP (vertical). The single nucleotide polymorphisms (SNPs) in the HbB gene (top) and G6PD gene (bottom) were targeted using DNA extracted from control samples and 90 individuals from the field.
| HbB | SSOP-ELISA | ||||||
| RFLP | HbAA | HbAS | HbSS | HbAC | HbCC | No PCR prod. | |
| HbAA | 74 | 1 | 1 | ||||
| HbAS | 11 | ||||||
| HbSS | 1 | ||||||
| HbAC | 1 | ||||||
| HbCC | 1 | ||||||
| No PCR-prod. | 3 | ||||||
| G6PD | SSOP-ELISA | ||||||
| RFLP | 68V | 68M | 68MV | 126N | 126D | 126DN | No PCR prod. |
| 68V | 64 | 2 | |||||
| 68M | 5 | ||||||
| 68MV | 2 | 8 | |||||
| 126N | 50 | 1 | |||||
| 126D | 14 | ||||||
| 126ND | 2 | 16 | |||||
| No PCR-prod. | 6 | ||||||
| Inconclusive | 4 | 2 | 2 | 2 | |||