Figure 3.
Cell cycle profiles for S.cerevisiae treated with 5-FU. Yeast were incubated in media with or without 150 µM 5-FU, fixed at given times with ethanol, and stained with propidium iodide. (A) Wild-type yeast treated with 5-FU arrest in the G1/S phase of the cell cycle. (B) Ung1 yeast arrest in G1/S phase of the cell cycle. (C) Apn1 yeast arrest in the G2/M phase of the cell cycle.