. 2006 Jan 10;34(1):e6. doi: 10.1093/nar/gnj002

Table 1.

BIOREL evaluation of PPI two hybrid data

Experiment	Network bias tested by BIOREL	BIOREL modules	Bias score^a
			Ito	Uetz	Overlapped, Ito+Uetz
1	Interacting proteins share the same function	FunCat module	0.1	0.18	0.30
2	Interacting proteins share sequence similarity (or partial similarity)	Sequence Similarity and InterPro Domain modules	0.05	0.10	0.15
3	Interacting proteins have the same length	Gene length module	∼0.01^b	∼0.01^b	∼0.01^b

^aThe bias score is a proportion of genes in the network with significantly (P < 0.01) biased associations.

^bThe biases were not found to be significant compared with random networks.