Table 4.
BIOREL evaluation of gene neighborhood networks in eu- and prokaryote genomes
| Genome | Network bias tested by BIOREL | BIOREL modules | Bias scorea | Top enriched categories |
|---|---|---|---|---|
| A.thaliana | Genes located closely on the chromosome have the same function or have similar sequences | FunCat module, Sequence Similarity and InterPro Domain modules | 0.20 | Sequence similarity (>90%) |
| B.subtilis | 0.22 | FunCat categories (>70%) | ||
| H.pylori | 0.18 | FunCat categories (>80%) | ||
| L.monocytogenes | 0.19 | FunCat categories (>70%) | ||
| T.acidophilum | 0.14 | FunCat categories (>50%) | ||
| S.cerevisiae | 0.04 | Sequence similarity (>60%) | ||
| N.crassa | 0.07 | Sequence similarity (>90%) |
aThe bias score is a proportion of genes in the network with significantly (P < 0.01) biased associations.