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. 2003 Jul;4(7):699–703. doi: 10.1038/sj.embor.embor883

Figure 3.

Figure 3

Structure-based sequence alignment of NTF2-like domains involved in nuclear transport. Sequence conservation is shown by colour coding. Invariant residues shared by Mex67 and TAP or shared by Mtr2 and p15 are highlighted in yellow. Residues that are conserved among NTF2-like folds are highlighted in orange. Secondary-structure elements of Mex67 and Mtr2 are indicated. The insertion region characteristic of nuclear export factor (NXF) proteins (Mex67 and TAP) is shaded in grey. The long internal loop present in the yeast Mex67 and Mtr2 proteins is also shaded in grey. Residues for which no ordered electron density is present are shown in italics. Residues contributing to Phe-Gly (FG) nucleoporin-binding sites (see also Fig. 4) are shown in blue.