Skip to main content
. 2003 Aug 15;4(9):883–888. doi: 10.1038/sj.embor.embor908

Figure 2.

Figure 2

T3 treatment increases histone H4 acetylation specifically at the T3-response elements of T3-response genes in pre-metamorphic tadpoles. Chromatin isolated from tail or intestine of T3-treated stage NF55 tadpoles (treated with 10 nM T3 for 48 h) was immunoprecipitated (IP) with antibodies against acetylated histone H4 (AcH4) and analysed by PCR, as described for Fig. 1. Each experiment was carried out at least twice. EF1a, elongation factor 1a; IFABP, intestinal fatty acid binding protein; T3, thyroid hormone (triiodothyronine); TH/bZIP, a basic leucine-zipper Th-response gene; TRb, thyroid hormone receptor b.