Figure 4.

Intimate interactions of hosts and pathogens. (A) The face of a smallpox victim in Accra, Ghana, 1967. (Photograph from the Center of Disease Control's Public Health Image Library.) (B) A poxvirus-infected cell is shown to illustrate just one of the many intricate ways in which pathogens can interact with, abuse or mimic their hosts. The virus is shown in red, the actin skeleton of the cell in green. Emerging viruses rearrange actin into tail-like structures that push them into neighbouring cells. (Image by F. Frischknecht and M. Way, reprinted with permission from the Journal of General Virology.)