Table 4.
Distribution of acute treatment responses according to Demographic and clinical characteristics
| Characteristics | Headache Attacks, N |
Acute Treatment Success | Acute Treatment Failure | Odds ratio (95% CI) | |||
|---|---|---|---|---|---|---|---|
| Pain freedom or relief within 1 hour | Pain freedom or relief within 2 hours | Pain freedom or relief within 4 hours | No Effect | Crude | Adjusted | ||
| Age group | |||||||
| 10s | 1,317 | 305 (23.2) | 194 (14.7) | 797 (60.5) | 21 (1.6) | 1.73 (1.55–1.94) | 0.53 (0.45–0.62) |
| 20s | 13,074 | 4,455 (34.1) | 2,982 (22.8) | 5,515 (42.2) | 122 (0.9) | 0.80 (0.77–0.84) | 0.75 (0.71–0.78) |
| 30s | 29,341 | 9,233 (31.5) | 6,367 (21.7) | 13,300 (45.3) | 441 (1.5) | 0.93 (0.90–0.96) | 1.00 (0.97–1.03) |
| 40s | 31,407 | 10,754 (34.2) | 5,383 (17.1) | 14,990 (47.7) | 280 (0.9) | (reference) | (reference) |
| 50s | 17,647 | 7,443 (42.2) | 2,832 (16.0) | 7,220 (40.9) | 152 (0.9) | 0.76 (0.73–0.79) | 0.87 (0.84–0.91) |
| 60s+ | 2,532 | 653 (25.8) | 650 (25.7) | 1,214 (47.9) | 15 (0.6) | 1.00 (0.92–1.08) | 1.02 (0.94–1.11) |
| Sex | |||||||
| Male | 13,410 | 4,118 (30.7) | 2,938 (21.9) | 6,270 (46.8) | 84 (0.6) | (reference) | (reference) |
| Female | 83,612 | 29,085 (34.8) | 15,858 (19.0) | 37,704 (45.1) | 965 (1.2) | 0.96 (0.92–1.00) | 0.92 (0.89–0.96) |
| Headache intensity | |||||||
| Mild | 26,267 | 9,163 (34.9) | 5,233 (19.9) | 11,755 (44.8) | 116 (0.4) | (reference) | (reference) |
| Moderate | 42,342 | 14,173 (33.5) | 8,258 (19.5) | 19,514 (46.1) | 397 (0.9) | 1.08 (1.04–1.11) | 1.07 (1.04–1.11) |
| Severe | 28,133 | 9,853 (35.0) | 5,305 (18.9) | 12,442 (44.2) | 533 (1.9) | 1.04 (1.00–1.07) | 0.98 (0.94–1.02) |
| Premonitory symptoms | 54,461 | 18,689 (34.3) | 11,115 (20.4) | 24,052 (44.2) | 605 (1.1) | 0.91 (0.89–0.94) | 0.97 (0.94–0.99) |
| Aura | 7,002 | 2,917 (41.7) | 1,226 (17.5) | 2,758 (39.4) | 101 (1.4) | 0.79 (0.75–0.83) | 0.78 (0.74–0.83) |
| Potential triggers | 69,841 | 24,480 (35.1) | 13,390 (19.2) | 31,152 (44.6) | 819 (1.2) | 0.93 (0.91–0.96) | 0.96 (0.93–0.99) |
| Type of treatment | |||||||
| Triptans | 86,301 | 32,928 (38.2) | 18,608 (21.6) | 33,804 (39.2) | 961 (1.1) | (reference) | (reference) |
| Other than triptans | 10,441 | 261 (2.5) | 188 (1.8) | 9907 (94.9) | 85 (0.8) |
32.99 (29.98–36.30) |
47.87 (39.23–58.41) |