Table 1.
Whole brain and regional Kin values × 104 at 45s in response to increasing unlabeled L-arginine concentrations. Data represent mean ± SEM for 3–4 mice
| Unidirectional and linear uptake of 3H-L-arginine in response to increasing concentrations of unlabled L-arginine | ||||||||
|---|---|---|---|---|---|---|---|---|
| Perfusate arginine concentration (µM) | ||||||||
| Region | 0.0047 | 25 | 35 | 50 | 100 | 150 | 350 | 450 |
| Whole Brain | 25 ± 0.2 | 17 ± 1.0 | 13 ± 1.9 | 9 ± 0.3 | 6 ± 0.6 | 4 ± 0.2 | 3 ± 0.4 | 2 ± 0.3 |
| Cortical | 17 ± 2.0 | 13 ± 1.0 | 13 ± 0.2 | 9 ± 1.8 | 6 ± 1.5 | 5 ± 0.3 | 3 ± 0.3 | 2 ± 0.3 |
| Subcortical | 19 ± 2.0 | 16 ± 0.6 | 14 ± 0.8 | 10 ± 0.9 | 8 ± 1.0 | 6 ± 0.4 | 3 ± 0.4 | 2 ± 0.4 |
| Cerebellum | 20 ± 3.0 | 17 ± 1.0 | 12 ± 1.7 | 15 ± 2.6 | 7 ± 0.7 | 8 ± 0.3 | 4 ± 0.6 | 3 ± 0.1 |