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Concentrations of linezolid or vancomycin (in serum) after continuous infusion
| Day | Concn (mg/liter) after administration of the following continuous infusion regimena:
|
||
|---|---|---|---|
| Linezolid
|
Vancomycin | ||
| 20 mg/kgb | 40 mg/kgc | ||
| 1 | 10.4 (1.6) | 27.1 (13.6) | ND |
| 2 | 19.4 (6.8) | 47.1 (18.8) | 22.3 (4.2) |
| 3 | 22.8 (4.2) | 49.7 (18.3) | ND |
| 5 | 32.5 (8.8) | 64.6 (6.3) | 25.1 (3.7) |
The values are means (standard deviations). ND, not done.
Simulated (daily) dose for humans.
Twice the recommended dose for humans.
