Table 3.
Values {Area under the ROC curves (AUROCs)} of SteatoTest, GGT and ALT for the diagnosis of steatosis greater than 5%, in both training and validation groups.
| Diagnostic panel | Training Group AUROC (se) | Validation Group 1 – HCV before treatment | Validation Group 2 – HCV sustained responders | Validation Group 3 – Alcoholic liver disease | All groups |
| N = 310 | N = 171 | N = 201 | N = 62 | N = 884 | |
| SteatoTest | 0.79 (0.03)* | 0.80 (0.04)£ | 0.86 (0.03) $ | 0.72 (0.05)** | 0.80 (0.02) ££ |
| GGT | 0.66 (0.03) | 0.67 (0.05) | 0.74 (0.05) | 0.50 (0.09) | 0.66 (0.02) |
| ALT | 0.58 (0.03) | 0.62 (0.05) | 0.79 (0.04) | 0.66 (0.07) | 0.61 (0.02) |
* – Higher than GGT (P < 0.0001) and ALT (P < 0.0001); £ – Higher than GGT (P = 0.007) and ALT (P < 0.0001); $ – Higher than GGT (P = 0.02); ** – Higher than GGT (P = 0.002); ££ Higher than GGT (P < 0.0001) and ALT (P < 0.0001).