TABLE 2.
Effects of serum and plasma at different concentrations on MIC80sa
| Microorganism | MIC80 (μg/ml) |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RPMI 1640 medium | Serum |
Inactivated serum |
Plasma |
Inactivated plasma |
|||||||||
| 10% | 20% | 50% | 10% | 20% | 50% | 10% | 20% | 50% | 10% | 20% | 50% | ||
| C. albicans | |||||||||||||
| 90028 | 0.0039 | 0.125 | 0.125 | 0.50 | 0.25 | 0.25 | 0.50 | 0.25 | 0.25 | 0.50 | 0.25 | 0.25 | 0.50 |
| 142.5609A | 0.0039 | 0.25 | 0.25 | 1.00 | 0.25 | 0.25 | 1.00 | 0.50 | 0.50 | 1.00 | 0.50 | 0.50 | 1.00 |
| 2733A | 0.0156 | 0.25 | 0.50 | 0.50 | 0.25 | 0.50 | 1.00 | 0.50 | 0.50 | 0.50 | 0.50 | 0.50 | 1.00 |
| OY-31.5 | 0.0039 | 0.125 | 0.125 | 0.50 | 0.25 | 0.25 | 0.50 | 0.25 | 0.25 | 0.50 | 0.25 | 0.25 | 0.50 |
| C. krusei | |||||||||||||
| 6258 | 0.25 | 1.00 | 2.00 | 4.00 | 1.00 | 1.00 | 4.00 | 1.00 | 2.00 | 4.00 | 2.00 | 2.00 | 4.00 |
| 37.5696A | 0.25 | 1.00 | 2.00 | 4.00 | 1.00 | 2.00 | 4.00 | 2.00 | 2.00 | 4.00 | 2.00 | 4.00 | 4.00 |
| C. tropicalis | |||||||||||||
| 2697 | 0.125 | 0.50 | 0.50 | 1.00 | 0.50 | 0.50 | 1.00 | 1.00 | 1.00 | 1.00 | 0.50 | 1.00 | 1.00 |
| 3829 | 0.0156 | 0.25 | 0.50 | NA | 0.50 | 0.50 | 1.00 | 0.50 | 0.50 | 1.00 | 0.50 | 1.00 | 1.00 |
The MIC80s were determined by the microdilution method, with the median MIC80s presented. NA, not available.