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. 2026 Jun 5;16:1820759. doi: 10.3389/fonc.2026.1820759

Table 2.

Clinical characterization of the study cohort.

Factor Total Alive* Deceased*
 N 14,425 9,733 4,692
Treatment outcome
 Unchanged 580 (4.0%) 580 (6.0%) 0 (0.0%)
 Recovery 3,410 (23.6%) 3,410 (35.0%) 0 (0.0%)
 Transferred to a 24-h hospital 4 (<1%) 4 (<1%) 0 (0.0%)
 Death 4,692 (32.5%) 0 (0.0%) 4,692 (100.0%)
 Improvement 4,401 (30.5%) 4,401 (45.2%) 0 (0.0%)
 Deterioration 1 (<1%) 1 (<1%) 0 (0.0%)
Missing 1,337 (9.3%) 1,337 (13.7%) 0 (0.0%)
Stage (TNM)
 I 5,100 (35.4%) 4,558 (46.8%) 542 (11.6%)
 II 6,085 (42.2%) 3,546 (36.4%) 2,539 (54.1%)
 III 1,913 (13.3%) 757 (7.8%) 1,156 (24.6%)
 IV 525 (3.6%) 98 (1.0%) 427 (9.1%)
 missing 802 (5.6%) 774 (8.0%) 28 (0.6%)
Stage (FIGO)
 I 5,248 (36.4%) 4,668 (48.0%) 580 (12.4%)
 II 6,337 (43.9%) 3,675 (37.8%) 2,662 (56.7%)
 III 1,597 (11.1%) 558 (5.7%) 1,039 (22.1%)
 IV 441 (3.1%) 58 (0.6%) 383 (8.2%)
missing 802 (5.6%) 774 (8.0%) 28 (0.6%)
ICD-10 code
 C53 1,219 (8.5%) 990 (10.2%) 229 (4.9%)
 C53.0 4,961 (34.4%) 3,501 (36.0%) 1,460 (31.1%)
 C53.1 3,478 (24.1%) 2,494 (25.6%) 984 (21.0%)
 C53.8 3,205 (22.2%) 1,839 (18.9%) 1,366 (29.1%)
 C53.9 1,562 (10.8%) 909 (9.3%) 653 (13.9%)
Hospitalization type
 Planned hospitalization 10,675 (74.0%) 7,094 (72.9%) 3,581 (76.3%)
 Emergency 239 (1.7%) 78 (0.8%) 161 (3.4%)
 Missing 3,511 (24.3%) 2,561 (26.3%) 950 (20.2%)
Morphological type of tumor
 Adenocarcinoma 970 (6.7%) 528 (5.4%) 442 (9.4%)
 Squamous cell carcinoma 10,807 (74.9%) 7,078 (72.7%) 3,729 (79.5%)
 Other 1,184 (8.2%) 744 (7.6%) 440 (9.4%)
 Missing 1,464 (10.1%) 1,383 (14.2%) 81 (1.7%)
Reason for late diagnosis
 Incomplete examination 29 (0.2%) 7 (0.1%) 22 (0.5%)
 Untimely medical examination 11 (0.1%) 1 (<1%) 10 (0.2%)
 Untimely referral 1,295 (9.0%) 396 (4.1%) 899 (19.2%)
 Refusal of examination 7 (<1%) 3 (<1%) 4 (0.1%)
 Error of other specialists 13 (0.1%) 5 (0.1%) 8 (0.2%)
 Clinical error 18 (0.1%) 5 (0.1%) 13 (0.3%)
 Latent course of disease 328 (2.3%) 100 (1.0%) 228 (4.9%)
 Missing 12,724 (88.2%) 9,216 (94.7%) 3,508 (74.8%)
Diagnosis circumstance
 In a female/male examination room 2,186 (15.2%) 1,425 (14.6%) 761 (16.2%)
 Self-referral 5,476 (38.0%) 3,074 (31.6%) 2,402 (51.2%)
 Under other circumstances 640 (4.4%) 388 (4.0%) 252 (5.4%)
 Under other types medical examination 3,267 (22.6%) 2,310 (23.7%) 957 (20.4%)
 During screening 1,657 (11.5%) 1,370 (14.1%) 287 (6.1%)
 Missing 1,199 (8.3%) 1,166 (12.0%) 33 (0.7%)
Disease status
 Local primary process 2,720 (18.9%) 1,485 (15.3%) 1,235 (26.3%)
 Metastatic/systemic process 6,571 (45.6%) 4,750 (48.8%) 1,821 (38.8%)
 New primary tumor 21 (0.1%) 14 (0.1%) 7 (0.1%)
 Remission/NED 304 (2.1%) 91 (0.9%) 213 (4.5%)
 Relapse (organ/extra organ) 58 (0.4%) 50 (0.5%) 8 (0.2%)

*By the time of registry download (11 October 2024).