Table 4.
Crude and adjusted hazard ratio predictors.
| Variable | Crude hazard ratio | Adjusted hazard ratio | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | AHR | 95% CI | P-value | |
| Age (10-year estimate) | 1.177 | [1.150, 1.205] | <0.001 | 1.219 | [1.187, 1.252] | <0.001 |
| Residence | ||||||
| Rural | Ref | |||||
| Urban | 0.834 | [0.786, 0.885] | <0.001 | 0.928 | [0.874, 0.985] | 0.014 |
| Hospitalization type | ||||||
| Planned | Ref | |||||
| Emergency | 2.731 | [2.332, 3.199] | <0.001 | 1.690 | [1.431, 1.995] | <0.001 |
| missing | 0.688 | [0.639, 0.740] | <0.001 | 1.333 | [1.176, 1.510] | <0.001 |
| Stage (TNM) | ||||||
| I | Ref | |||||
| II | 4.854 | [4.423, 5.327] | <0.001 | 3.601 | [3.253, 3.987] | <0.001 |
| III | 9.107 | [8.220, 10.091] | <0.001 | 6.143 | [5.501, 6.860] | <0.001 |
| IV | 21.022 | [18.498, 23.890] | <0.001 | 13.415 | [11.710, 15.368] | <0.001 |
| missing | 0.081 | [0.040, 0.163] | <0.001 | 0.059 | [0.030, 0.120] | <0.001 |
| Treatment | ||||||
| Surgery | Ref | |||||
| Chemotherapy | 6.213 | [5.240, 7.365] | <0.001 | 1.949 | [1.631, 2.330] | <0.001 |
| Combined (radiation+chemotherapy) | 5.179 | [4.448, 6.031] | <0.001 | 1.793 | [1.525, 2.108] | <0.001 |
| Combined (surgery+chemotherapy+radiation) | 4.437 | [3.760, 5.235] | <0.001 | 1.817 | [1.529, 2.160] | <0.001 |
| Combined (surgery+chemotherapy) | 4.751 | [3.818, 5.911] | <0.001 | 1.903 | [1.521, 2.381] | <0.001 |
| Combined (surgery+radiation) | 1.355 | [1.092, 1.681] | 0.006 | 1.032 | [0.831, 1.282] | 0.777 |
| Immunotherapy | 8.776 | [2.179, 35.345] | 0.002 | 5.150 | [1.275, 20.804] | 0.021 |
| Missing | 2.656 | [2.282, 3.090] | <0.001 | 1.464 | [1.221, 1.755] | <0.001 |
| Other | 4.452 | [1.654, 11.982] | 0.003 | 1.394 | [0.517, 3.762] | 0.511 |
| Radiation | 4.876 | [4.133, 5.752] | <0.001 | 1.914 | [1.610, 2.276] | <0.001 |
| Symptomatic | 11.248 | [9.332, 13.558] | <0.001 | 3.279 | [2.694, 3.990] | <0.001 |
| Comorbidities | ||||||
| Cardiovascular diseases | 0.762 | [0.718, 0.809] | <0.001 | 0.680 | [0.637, 0.726] | <0.001 |
| Metabolic endocrine disorders | 0.728 | [0.667, 0.794] | <0.001 | 0.849 | [0.775, 0.929] | <0.001 |
| Genitourinary reproductive | 1.499 | [1.415, 1.588] | <0.001 | 1.402 | [1.322, 1.487] | <0.001 |
| Hematologic immune diseases | 1.901 | [1.761, 2.051] | <0.001 | 1.578 | [1.459, 1.706] | <0.001 |
| Infectious parasitic | 0.758 | [0.693, 0.830] | <0.001 | 0.837 | [0.763, 0.917] | <0.001 |
| Mental behavioral | 1.873 | [1.671, 2.100] | <0.001 | 1.636 | [1.457, 1.838] | <0.001 |
| Abnormal symptom signs | 1.955 | [1.721, 2.220] | <0.001 | 1.315 | [1.154, 1.497] | <0.001 |
| Neoplasms non-malignant | 0.576 | [0.504, 0.658] | <0.001 | 0.717 | [0.627, 0.820] | <0.001 |