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. 2026 Jun 5;17:1868650. doi: 10.3389/fimmu.2026.1868650

Table 2.

Comparison of baseline characteristics between the training set and the test set.

Characteristic Training set (n = 849) Test set (n = 286) P value
Age (years) 63.08 ± 13.34 62.74 ± 13.02 0.708
NAR 1.75 ± 0.37 1.75 ± 0.38 0.884
Complement C3 (g/L) 1.13 ± 0.20 1.15 ± 0.22 0.166
Complement C4 (g/L) 0.38 ± 0.12 0.39 ± 0.12 0.698
Globulin (g/L) 26.33 ± 3.65 26.18 ± 3.54 0.530
HDL (mmol/L) 1.28 ± 0.35 1.30 ± 0.35 0.538
VZV-IgA (g/L) 2.37 ± 0.97 2.45 ± 1.10 0.232
VZV-IgG (g/L) 13.86 ± 3.69 13.47 ± 3.40 0.109
LDL (mmol/L) 2.76 ± 0.89 2.77 ± 0.91 0.964
Neutrophil percentage (%) 63.00 ± 12.18 64.16 ± 12.04 0.959
Albumin (g/L) 36.46 ± 3.48 36.44 ± 3.17 0.091
Eosinophil percentage (%) 1.77 ± 1.98 1.59 ± 2.03 0.682
Time to treatment (days) 6 (4, 10) 6 (4, 10) 0.997
Eosinophil count (×109/L) 0.07 (0.01, 0.13) 0.06 (0.01, 0.13) 0.441
hs-CRP (mg/L) 0.5 (0.5, 3.7) 0.7(0.5,3.2) 0.540
WBC (×109/L) 5.4 (4.4, 6.7) 5.4(4.4,6.75) 0.996
Lymphocyte count (×109/L) 1.38 (1, 1.82) 1.31(0.91,1.755) 0.140
Monocyte count (×109/L) 0.42 (0.31, 0.55) 0.41(0.3,0.535) 0.305
Neutrophil count (×109/L) 3.31(2.53, 4.48) 3.46(2.54,4.67) 0.476
NLR 2.4(1.61,3.8925) 2.6(1.63,4.07) 0.138
CLR 0.58(0.28,2.695) 0.67(0.3,2.835) 0.410
SIRI 0.95 (0.6, 1.52) 1.08 (0.65, 1.72) 0.098
NSE (ng/mL) 9.55 (8.16, 10.87) 9.35 (8.35, 10.75) 0.554
Creatinine (μmol/L) 62 (53, 74) 60 (51, 72.5) 0.136
VZV-IgM (g/L) 0.82 (0.53, 1.21) 0.81 (0.54, 1.285) 0.450
Sex, n (%) Male 385 (74.8) 130 (25.2) 0.925
Female 465 (75) 155 (25)
NRS score, n (%) 0 1 (100) 0 (0) 0.448
1 52 (66.7) 26 (33.3)
2 243 (77.4) 71 (22.6)
3 173 (72.4) 66 (27.6)
4 155 (76.4) 48 (23.6)
5 112 (79.4) 29 (20.6)
6 49 (70) 21 (30)
7 39 (76.5) 12 (23.5)
8 18 (72) 7 (28)
9 7 (58.3) 5 (41.7)
10 1 (100) 0 (0)
Prodromal pain, n (%) No 570 (75.5) 185 (24.5) 0.506
Yes 280 (73.7) 100 (26.3)
Rash location, n (%) Cephalic-facial 258 (75.2) 85 (24.8) 0.420
Thoracodorsal 251 (77.2) 74 (22.8)
Lumbabdominal 163 (73.4) 59 (26.6)
Cervicoscapular 41 (66.1) 21 (33.9)
Upper limb 51 (79.7) 13 (20.3)
Lower limb 86 (72.3) 33 (27.7)
Hypertension, n (%) No 522 (74.9) 175 (25.1) 0.998
Yes 328 (74.9) 110 (25.1)
Diabetes, n (%) No 724 (75.1) 240 (24.9) 0.693
Yes 126 (73.7) 45 (26.3)
Malignancy, COPD or CKD, n (%) No 730 (74.4) 251 (25.6) 0.351
Yes 120 (77.9) 34 (22.1)
Antidepressant or anxiolytic medication use, n (%) No 816 (74.7) 276 (25.3) 0.519
Yes 34 (79.1) 9 (20.9)
Anxiety or depression, n (%) No 832 (74.8) 281 (25.2) 0.449
Yes 18 (81.8) 4 (18.2)
Sleep disorder, n (%) No 394 (74.5) 135 (25.5) 0.766
Yes 456 (75.2) 150 (24.8)
Immunosuppressive status, n (%) No 807 (75) 269 (25) 0.715
Yes 43 (72.9) 16 (27.1)