Table 2. Logistic regression model showing variables associated with relapse status.
|
Variable |
OR |
95% CI |
p-value |
|
ESR >20 mm/h |
2.45 |
1.10–5.46 |
0.023 |
|
CRP ≥5 mg/L |
1.95 |
0.98–4.22 |
0.056 |
|
TNF-a inhibitor |
4.87 |
1.70–13.90 |
<0.001 |
|
Cyclosporine |
3.85 |
1.48–10.03 |
0.006 |
|
Azathioprine |
- |
- |
0.494(no relapses observed) |
|
Age |
0.98 |
0.93–1.03 |
0.398 |
|
Surgical intervention |
1.55 |
0.82–2.91 |
0.184 |
|
ACE >52 U/L |
2.26 |
1.12–4.53 |
0.010 |
TNF-a inhibitors and cyclosporine were used as rescue therapy in relapsing/refractory cases; therefore, their statistical associations with relapse should be interpreted cautiously due to confounding by indication, TNF-a: Tumor necrosis factor alpha; OR: Odds ratio; CI: Confidence interval; ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein